Course Catalog

Description

Course given only for Biotechnology Bachelor students The first part of the course will cover the basic outline of the gene structure and the expression of genes in prokaryotic and eukaryotic cells. The structure of polycistronic operons, the regulation of expression (induction and repression and translational control) and the structure of ribosomes and mechanisms of translation will be covered. Also the organisation of eukaryotic chromosomes and chromatin, genes, mechanisms of transcription and the regulation of transcription, splicing of mRNA precursors, alternative splicing, poly-adenylation and termination in eukaryotic cells will be discussed The second part of the course introduces the concepts of Mendelian genetics including monohybrid and dihybrid crossing as well as its statistical analysis and Mendelian human genetics. Further, the chromosomal basis of inheritance with particular focus on mitosis and meiosis and the chromosome theory of inheritance will be discussed. Analysis of gene mapping in eucaryotes, bacteria and bacteriophages will be covered. Finally, eucaryotic model organisms in genetics will be introduced.