Course Catalog

Description

Biopharmaceutical principles concerning the release from dosage forms, absorption, distribution, metabolism, and excretion of drugs, reaction kinetics (kinetics of drug degradation in vivo and in vitro), plasma concentration-time curves, multi-dosage principles, bioavailability, bioequivalence, in vitro/in vivo correlations. Pharmacokinetic basis for the development and testing of pharmaceutical products (pharmacokinetic models and parameters). Storage conditions and their effect on stability, methods of stability testing. Controlled-release vs. immediate-release preparations. The exercises during the tutorials include the analysis of drug degradation processes, in-vitro/in-vivo correlations, parameters derived from different compartmental kinetic models, parameters for drug absorption and bioavailability.